The SPCG brings together the expertise of healthcare professionals (endocrinologists, neurosurgeons, pathologists, radiologists, radiation oncologists, medical oncologists, trainees) interested in advancing pituitary tumour management, education and research through collaboration.
The group is led by Dr Ann McCormack, of the Garvan Institute of Medical Research and St Vincent's Hospital, Sydney.

 

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Familial Pituitary Tumour Project

This project involves the identification of inherited genetic mutations that may be responsible for causing pituitary adenomas in the Australian population.

What genes are under investigation in this project?

1. aryl hydrocarbon receptor interacting protein (AIP)

2. multiple endocrine neoplasia (MEN-1)

3. cyclin-dependent kinase inhibitor 1B (p27)

4. new genes             

Why are we doing this project?

Identifying these mutations amongst patients with possible predisposition to pituitary tumours will help guide clinicians towards appropriate screening. Early recognition of these disorders will allow early detection for family members and guide treatment for affected individuals.

How will the project work?

Over the next 2 years, approximately 200 consenting participants will be recruited. Participants will be selected based on meeting specific criteria (see below).

Where will the project be conducted?

The Garvan Institute of Medical Research – Darlinghurst, NSW (Principal site)

Am I eligible?

We are looking for people

1. who have been diagnosed with a pituitary tumour under the age of 40,

and/or

2. with a family history of pituitary tumours,

and/or

3. already known to carry an MEN-1 or AIP mutation on genetic testing

How do I get involved?

If you are interested in participating, please contact Tanya at: 

pituitaryresearch@garvan.org.au

 

 




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8.15am 29/07/2017
Princess Alexandra Hospital, Queensland
 
 

   
 

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